Purpose/Significance To systematically review the application of large language model(LLM)in the biomedical aca-demic service platform，and to provide references for constructing a trustworthy and intelligent academic service system. Method/Pro. cess A three-dimensional analytical framework of“technology-domain-scenario”is constructed. Ten representative domestic and inter-national biomedical academic service platforms are selected. Analysis is conducted across technical pathways，functional distributions and resource ecosystems to reveal the structural differences in the intelligent evolution of various platforms. Result/Conclusion The dif-ferences in functions and technical paths between domestic and foreign platforms are shaped by language structures，terminological stan-dards and corpus conditions within their respective ecological backgrounds. Future efforts should be made to enhance multimodal fusion， develop reliable generation paths for knowledge enhancement，and promote the construction of a compliant closed-loop ecosystem to em-power scientific research and innovation.